Toothpaste Formulation Ethanol Extract Mangosteen Peel (Garcinia mangostana L.) and Test Activity Against Candida Albicans

The mangosteen peel contains phenol compounds that have antifungal activity. study aimed to find out the activity in dosage form of toothpaste against Candida albicans. research methods used include extraction (Garcinia mangostana L.) by maceration using 96% ethanol. formula was composed with an extract concentration 1.25% (F1); 2.5% (F2); 5% (F3); and base (B). Antifungal testing carried diffusion method Potato Dextrose Agar (PDA) media. results showed a F1; F2; F3; (B) has average value successive inhibition zone diameters 11.86 mm; 12.03mm; 12.54mm; 7.78 mm. conclusion preparation ethanol fruit 1.25%; 2.5%; which performs